Ipamorelin

Summary

Ipamorelin is a synthetic pentapeptide and selective growth-hormone secretagogue (a ghrelin/GHS-R agonist) studied for stimulating growth-hormone release with minimal effect on cortisol or prolactin in research settings. It is a research compound.

Quick facts

Also known asNNC 26-0161
CategoryGH secretagogue
StatusResearch
FormulaC38H49N9O5
Molecular weight711.85 g/mol
SequenceAib-His-D-2-Nal-D-Phe-Lys-NH2
Half-life~2 hours (reported)
StorageLyophilized: cool & dark, long-term −20°C. Reconstituted: 2–8°C, use within a few weeks.

How it works

Ipamorelin mimics ghrelin at the growth-hormone secretagogue receptor (GHS-R), prompting the pituitary to release growth hormone in pulses. In research it is noted for being relatively selective, with little reported impact on cortisol or prolactin compared with some earlier secretagogues.

Reported effects in the literature

Studies describe dose-dependent increases in growth-hormone levels. Evidence is largely preclinical and early-stage; this is not medical guidance.

References

Tools

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For informational use only. Not medical advice; consult a qualified healthcare professional. 21+.